Study # INSPIRE-CRT

Incentive Spirometry for Respiratory Enhancement (INSPIRE-CRT) pilot Clinical Trial in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy

Study Status:

Enrolling

Treatment Agent:

Not Applicable

Description

Short Title: INSPIRE-CRT

The INSPIRE-LUNG-CRT trial is a prospective, pilot study investigating the efficacy of incentive spirometry on the incidence and severity of pneumonitis in lung cancer patients undergoing concurrent chemotherapy and radiation therapy with immunotherapy maintenance. Despite advancements in treatment modalities, pulmonary complications remain a significant challenge, often leading to diminished functional capacity and quality of life. This trial aims to establish incentive spirometry as a non-pharmacological intervention to reduce these complications, thereby improving clinical outcomes and patient well-being. Lung cancer treatments are frequently associated with pulmonary toxicities, such as radiation-induced pneumonitis and fibrosis, immunotherapy induced pneumonitis, significantly impacting patient outcomes. Incentive spirometry, a device that encourages deep breathing and lung expansion, has shown promise in postoperative settings but is underutilized in oncology.

Resources and Links

National Clinical Trial Identified Number: NCT06688422

Information and next steps

Disease:

  • Lung Cancer,
  • Non-Small-Cell Lung Cancer (NSCLC)

Study Phase:

III

Physician Name:

Department:

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