A022104
Short Title: JANUS
This phase II trial compares the effect of irinotecan versus oxaliplatin after long-course chemoradiation in patients with stage II-III rectal cancer. Combination chemotherapy drugs, such as FOLFIRINOX (fluorouracil, irinotecan, leucovorin, and oxaliplatin), FOLFOX (leucovorin, fluorouracil, oxaliplatin, and irinotecan), and CAPOX (capecitabin and oxaliplatin) work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Study Number:
A022104
Study Status:
Enrolling
Treatment Agent:
Capecitabine, 5-fluorouracil, Leucovorin calcium, Irinotecan, Oxaliplatin
Resources and Links
National Clinical Trial Identified Number: NCT05610163
Disease:
- Locally Advanced Rectal Carcinoma
Study Phase:
II
researchcancer@cooperhealth.edu
Article Title
A Randomized Phase II Trial Testing the Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients with Locally Advanced Rectal Cancer
Index Extra:
GI, gastro, rectal
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Department:
SURVENT
Short Title: SURVENT
The trial’s primary aim is to determine if patients undergoing endoscopic eradication therapy will demonstrate less neoplastic progression and a lower incidence of esophageal adenocarcinoma compared to patients undergoing surveillance.
Study Number:
SURVENT
Study Status:
Enrolled
Treatment Agent:
Not Applicable
Resources and Links
National Clinical Trial Identified Number: NCT05753748
Disease:
- Barrett’s Esophagus with Low-grade Dysplasia,
- Esophageal Adenocarcinoma
Study Phase:
Not Applicable
researchcancer@cooperhealth.edu
Article Title
A Multicenter Randomized Controlled Trial of Surveillance vs. Endoscopic Therapy for Barrett’s Esophagus with Low-grade Dysplasia
Index Extra:
Esophageal, head and neck, Dysplasia, Barrett’s, Esophagus, gastro
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